Tissue-specific sorting-out in two dimensions in relation to contact inhibition of cell movement.

摘要: IT is thought that the monolayering of cells which takes place on a substratum in tissue culture results from “contact inhibition cell movement”, movement direction contact with another1. If it toward contacted neighbour inhibited, are surrounded all sides by other should be immobilized2. Yet heterotypic aggregates must and do move course tissue-specific sorting out, even though they directions cells3,4. Because this we wondered whether movement” requires solid substratum. We decided to see different origin combined mixed monolayer would immobilized prevented sorting-out.