Laser and light therapies for the treatment of nail psoriasis.

摘要: Psoriatic involvement of the nail is notoriously refractory to conventional therapy. Nail psoriasis has a high incidence amongst patients with psoriasis. It remains significant cosmetic problem and thus, impact on quality life. More recently, light laser therapies have emerged as modalities for treatment In this study, efficacies are systematically reviewed. Light involve ultraviolet (with or without photosensitizers) intense pulsed light. Alternatively, therapy in primarily administered using 595-nm dye laser. These demonstrated improvement psoriatic lesions, even complete resolution some cases. Both also been tested combination other systemic topical therapeutics, variable efficacy. generally well tolerated. Side-effects include hyperpigmentation, itching erythema; whereas, side-effects more frequent pain, purpura/petechiae hyperpigmentation. Patterns response were seen based presenting characteristics lesions: subungual hyperkeratosis onycholysis appeared be most responsive therapy, while pitting was resistant. potential an efficient cost-effective in-office However, large-scale clinical trials needed assess their efficacy, particularly therapeutic modalities.