Test of Compton camera components for prompt gamma imaging at the ELBE bremsstrahlung beam

作者: F Hueso-González , C Golnik , M Berthel , A Dreyer , W Enghardt

DOI: 10.1088/1748-0221/9/05/P05002

关键词:

摘要: In the context of ion beam therapy, particle range verification is a major challenge for quality assurance treatment. One approach measurement prompt gamma rays resulting from tissue irradiation. A Compton camera based on several position sensitive ray detectors, together with an imaging algorithm, expected to reconstruct emission density map, which correlated dose distribution. At OncoRay and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), setup being developed consisting two scatter planes: CdZnTe (CZT) cross strip absorber one Lu2SiO5 (LSO) block detector. The data acquisition VME electronics handled by software ROOT framework. has been tested at linear electron accelerator ELBE HZDR, used in this experiment produce bunched bremsstrahlung photons up 12.5 MeV energy repetition rate 13 MHz. Their spectrum similarities shape clinical environment, flux also frequency. charge sharing effect CZT detector studied qualitatively different ranges. LSO pixel discrimination resolution analyzed it shows trend improve high depositions. time correlation between pulsed measured signals, be background suppression, exhibits 3 ns FWHM 2 walk correction pixel-wise calibration applied detector, whose improves 630 ps. conclusion, suitable time-resolved suppression accelerators. Ongoing tasks are quantitative comparison simulations test algorithms. Experiments proton accelerators have performed currently under analysis.

参考文章(17)
Rene Brun, Fons Rademakers, ROOT — An object oriented data analysis framework Nuclear Instruments & Methods in Physics Research Section A-accelerators Spectrometers Detectors and Associated Equipment. ,vol. 389, pp. 81- 86 ,(1997) , 10.1016/S0168-9002(97)00048-X
T. Kormoll, F. Fiedler, C. Golnik, K. Heidel, M. Kempe, S. Schone, M. Sobiella, K. Zuber, W. Enghardt, A prototype Compton camera for in-vivo dosimetry of ion beam cancer irradiation international conference on advancements in nuclear instrumentation, measurement methods and their applications. pp. 1- 3 ,(2011) , 10.1109/ANIMMA.2011.6172961
F Roellinghoff, A Benilov, D Dauvergne, G Dedes, N Freud, G Janssens, J Krimmer, J M Létang, M Pinto, D Prieels, C Ray, J Smeets, F Stichelbaut, E Testa, Real-time proton beam range monitoring by means of prompt-gamma detection with a collimated camera Physics in Medicine and Biology. ,vol. 59, pp. 1327- 1338 ,(2014) , 10.1088/0031-9155/59/5/1327
Robert R. Wilson, Radiological Use of Fast Protons Radiology. ,vol. 47, pp. 487- 491 ,(1946) , 10.1148/47.5.487
Antje-Christin Knopf, Antony Lomax, In vivo proton range verification: a review Physics in Medicine and Biology. ,vol. 58, ,(2013) , 10.1088/0031-9155/58/15/R131
A. Müller, F. Fiedler, D. Georg, J. Hopfgartner, W. Enghardt, 118 IN-BEAM SPECT BASED IN VIVO DOSIMETRY: FROM TREATMENT PLANNING TO MEASURED DOSE Radiotherapy and Oncology. ,vol. 102, ,(2012) , 10.1016/S0167-8140(12)70090-7
K.A. Stonger, M.T. Johnson, Optimal calibration of PET Crystal position maps using Gaussian mixture models IEEE Transactions on Nuclear Science. ,vol. 51, pp. 85- 90 ,(2004) , 10.1109/TNS.2004.823334
Y. Okada, T. Takahashi, G. Sato, S. Watanabe, K. Nakazawa, K. Mori, K. Makishima, CdTe and CdZnTe detectors for timing measurements ieee nuclear science symposium. ,vol. 49, pp. 1986- 1992 ,(2001) , 10.1109/TNS.2002.801709
P.N. Luke, Unipolar charge sensing with coplanar electrodes-application to semiconductor detectors ieee nuclear science symposium. ,vol. 42, pp. 207- 213 ,(1995) , 10.1109/23.467848
Chan Hyeong Kim, Kyu Seok Seo, Jong Won Kim, Comparison of Titanium Hydride (TiH2) and Paraffin as Neutron Moderator Material in a Prompt Gamma Scanning System Journal of the Korean Physical Society. ,vol. 48, pp. 855- 858 ,(2006)