A mutation in the ribosomal protein L3 confers resistance to Deoxynivalenol in transgenic tobacco

摘要: Mycotoxins belonging to the class of trichothecenes act primarily as inhibitors eukaryotic protein synthesis. Gene disruption studies indicate that production deoxynivalenol (DON), a member trichothecenes, is virulence factor Fusarium graminearum. The probable role toxin inhibit active defense responses plant by interfering with expression related proteins and condition host for colonization. Correlative evidence available resistance significantly contributes field wheat. It was shown in yeast trichodermin (also trichothecenes) binds component 60S subunit wildtype ribosome (Barbacid Vazquez, 1974) gene TCM1, which found encode ribsomal L3 (RPL3), responsible semidominant (SCHULTZ FRIESEN, 1983).