Diterpenoids and phenanthrenones from the leaves and stems of Strophioblachia fimbricalyx

摘要: Abstract Five new compounds, namely fimbricalyxoids A–D (1–4) and 13-O-methylfimbricalyx B (5), together with five known compounds (6–10) were isolated from the leaves stems of Strophioblachia fimbricalyx. Fimbricalyxoid A (1), a cleistanthane diterpenoid, possesses rare 3,20-oxybridge, while C–D (3–4) are first seco-ring-A pentanorditerpenoids. Their structures absolute configuration established based on NMR MS data ECD calculation (1). Compounds 1, 6, 7 exhibited cytotoxicity against human tumor cell lines IC50 values in range 1.4–8.2 μM.