Seasonal allergic rhinitis.

作者: A. Parikh , G. K Scadding

DOI: 10.1136/BMJ.314.7091.1392

关键词:

摘要: Seasonal allergic rhinitis or hay fever was called “catarrhus aestivus” (spring catarrh) in 19th century medical literature, but more recently has been labelled as a “post industrial revolution epidemic.”1 Its prevalence increased developed countries, particularly the past two decades.2 One six people is affected by rhinitis.3 In 1990 estimated cost of United States $1.8 billion.4 Effective medication for this condition available, and prophylactic treatment (topical corticosteroids, sodium cromoglycate) should be started to three weeks before pollen season prevent priming allergen. This year warm spring advanced earlier. After concern over risk cardiac arrhythmias, Medicines Control Agency currently converting terfenadine, commonly used antihistamine that available counter, into prescription only drug. Most articles selected were from personal library GKS, who 10 years clinical research experience subject. For an overview, we book chapters had written leaders subject, while individual papers details particular aspects seasonal rhinitis. Drug related came British National Formulary , manufacturers' product data, documents Agency. Seasonal type I immediate hypersensitivity reaction mediated specific IgE antibody allergen, leading mucosal inflammation characterised sneezing, itching, rhinorrhoea, nasal blockage. Pollens wind pollinated grasses, trees, weeds, spores fungi are commonest aeroallergens. male gametes plants, most antigenic pollens 6-40 μm diameter. Larger oil seed rape, which insects, have …

参考文章(28)
Deyun Wang, Peter Clement, Johan Smitz, Marie-Paule Derde, Concentrations of chemical mediators in nasal secretions of patients with hay fever during natural allergen exposure. Acta Oto-laryngologica. ,vol. 114, pp. 552- 555 ,(1994) , 10.3109/00016489409126103
CM Dixon, PJ Barnes, Bradykinin-induced bronchoconstriction: inhibition by nedocromil sodium and sodium cromoglycate. British Journal of Clinical Pharmacology. ,vol. 27, pp. 831- 836 ,(1989) , 10.1111/J.1365-2125.1989.TB03446.X
J. Bousquet, H. Maasch, B. Martinot, A. Hejjaoui, R. Wahl, F.B. Michel, Double-blind, placebo-controlled immunotherapy with mixed grass-pollen allergoids. II. Comparison between parameters assessing the efficacy of immunotherapy. The Journal of Allergy and Clinical Immunology. ,vol. 82, pp. 439- 446 ,(1988) , 10.1016/0091-6749(88)90017-6
J. Emberlin, Plant Allergens on Pauci-Micronic Airborne Particles Clinical & Experimental Allergy. ,vol. 25, pp. 202- 205 ,(1995) , 10.1111/J.1365-2222.1995.TB01029.X
Toyoko Nakagomi, Hideki Itaya, Tooru Tominaga, Mitsuo Yamaki, Shun-ichi Hisamatsu, Osamu Nakagomi, Is atopy increasing The Lancet. ,vol. 343, pp. 121- 122 ,(1994) , 10.1016/S0140-6736(94)90854-0
S. Romagnani, Human TH1 and TH2 subsets : regulation of differentiation and role in protection and immunopathology International Archives of Allergy and Immunology. ,vol. 98, pp. 279- 285 ,(1992) , 10.1159/000236199
George W. Hagy, Guy A. Settipane, Bronchial asthma, allergic rhinitis, and allergy skin tests among college students Journal of Allergy. ,vol. 44, pp. 323- 332 ,(1969) , 10.1016/0021-8707(69)90024-0
C. McSharry, Oilseed rape sensitivity Clinical & Experimental Allergy. ,vol. 27, pp. 125- 127 ,(1997) , 10.1111/J.1365-2222.1997.TB00683.X
D M Fleming, D L Crombie, Prevalence of asthma and hay fever in England and Wales. BMJ. ,vol. 294, pp. 279- 283 ,(1987) , 10.1136/BMJ.294.6567.279