摘要: Seasonal allergic rhinitis or hay fever was called “catarrhus aestivus” (spring catarrh) in 19th century medical literature, but more recently has been labelled as a “post industrial revolution epidemic.”1 Its prevalence increased developed countries, particularly the past two decades.2 One six people is affected by rhinitis.3 In 1990 estimated cost of United States $1.8 billion.4 Effective medication for this condition available, and prophylactic treatment (topical corticosteroids, sodium cromoglycate) should be started to three weeks before pollen season prevent priming allergen. This year warm spring advanced earlier. After concern over risk cardiac arrhythmias, Medicines Control Agency currently converting terfenadine, commonly used antihistamine that available counter, into prescription only drug. Most articles selected were from personal library GKS, who 10 years clinical research experience subject. For an overview, we book chapters had written leaders subject, while individual papers details particular aspects seasonal rhinitis. Drug related came British National Formulary , manufacturers' product data, documents Agency. Seasonal type I immediate hypersensitivity reaction mediated specific IgE antibody allergen, leading mucosal inflammation characterised sneezing, itching, rhinorrhoea, nasal blockage. Pollens wind pollinated grasses, trees, weeds, spores fungi are commonest aeroallergens. male gametes plants, most antigenic pollens 6-40 μm diameter. Larger oil seed rape, which insects, have …