The development of catalepsy in drug-free mice on repeated testing

作者: Janet Brown , Sheila L. Handley

DOI: 10.1016/0028-3908(80)90043-X

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摘要: Abstract When subjected to repeated testing for catalepsy, 24% of mice retained the imposed posture more than 5 seconds at 8th trial compared with 1.21% first. Median retention time ‘trained’ was O first trial, rising 12 8th. During retention, animals closely resembled treated haloperidol in showing moderate rigidity lateral configurations tail. Posture thus deserves be called catalepsy. Preliminary experiments suggest that it is reduced by atropine and apomorphine but not naloxone. The significance phenomenon discussed.

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