Three-year prospective, observational study of central line-associated bloodstream infections in a 600-bed Japanese acute care hospital.

作者: Yasuko Matsui , Michitsugu Shimatani , Kenta Kuzuhara , Yoshiko Miyazaki , Tomoko Horiuchi

DOI: 10.1016/J.AJIC.2015.01.011

关键词:

摘要: Background Central line–associated bloodstream infection (CLABSI) is an important concern associated with central venous catheter (CVC) use. The objective of this study was to determine the influences CVC access sites, types, and presumed causative microorganisms on CLABSI occurrence in acute care hospital. Methods We conducted a prospective, observational for 3 consecutive years 600-bed Japanese Data collected included patient characteristics, isolated by blood culture. Results For 1,650 CVCs used 1,237 patients, 39 cases were identified. Most infections had occurred within 1 month insertion. Maximal sterile barrier precautions been most (97.3%). average days internal jugular vein shorter than those subclavian femoral access. rates 1.1 0.7 single- multilumen CVCs, respectively. tended be when gram-positive cocci longer fungi (Candida spp) isolated. Conclusion Longer duration increased chance fungal infection.

参考文章(23)
ROBERT B. LEE, MARTHA BUCKNER, KENNETH W. SHARP, Do multi-lumen catheters increase central venous catheter sepsis compared to single-lumen catheters? Journal of Trauma-injury Infection and Critical Care. ,vol. 28, pp. 1472- 1475 ,(1988) , 10.1097/00005373-198810000-00012
Cameron Dezfulian, James Lavelle, Brahmajee K. Nallamothu, Samuel R. Kaufman, Sanjay Saint, Rates of infection for single-lumen versus multilumen central venous catheters: A meta-analysis Critical Care Medicine. ,vol. 31, pp. 2385- 2390 ,(2003) , 10.1097/01.CCM.0000084843.31852.01
R Krause, T Valentin, H Salzer, M Hönigl, A Valentin, H Auner, I Zollner-Schwetz, None, Which lumen is the source of catheter-related bloodstream infection in patients with multi-lumen central venous catheters? Infection. ,vol. 41, pp. 49- 52 ,(2013) , 10.1007/S15010-012-0391-X
Ryan P. Fagan, Jonathan R. Edwards, Benjamin J. Park, Scott K. Fridkin, Shelley S. Magill, Incidence trends in pathogen-specific central line-associated bloodstream infections in US intensive care units, 1990-2010. Infection Control and Hospital Epidemiology. ,vol. 34, pp. 893- 899 ,(2013) , 10.1086/671724
A. Templeton, M. Schlegel, F. Fleisch, G. Rettenmund, B. Schöbi, S. Henz, G. Eich, Multilumen Central Venous Catheters Increase Risk for Catheter-Related Bloodstream Infection: Prospective Surveillance Study Infection. ,vol. 36, pp. 322- 327 ,(2008) , 10.1007/S15010-008-7314-X
Jean-Jacques Parienti, Marina Thirion, Bruno Mégarbane, Bertrand Souweine, Abdelali Ouchikhe, Andrea Polito, Jean-Marie Forel, Sophie Marqué, Benoît Misset, Norair Airapetian, Claire Daurel, Jean-Paul Mira, Michel Ramakers, Damien du Cheyron, Xavier Le Coutour, Cédric Daubin, Pierre Charbonneau, for Members of the Cathedia Study Group, Femoral vs jugular venous catheterization and risk of nosocomial events in adults requiring acute renal replacement therapy: a randomized controlled trial. JAMA. ,vol. 299, pp. 2413- 2422 ,(2008) , 10.1001/JAMA.299.20.2413
Mandakini Pawar, Yatin Mehta, Pawan Kapoor, Jitendra Sharma, Abhinav Gupta, Naresh Trehan, Central venous catheter—related blood stream infections: incidence, risk factors, outcome, and associated pathogens Journal of Cardiothoracic and Vascular Anesthesia. ,vol. 18, pp. 304- 308 ,(2004) , 10.1053/J.JVCA.2004.03.009
K. K. Hu, D. L. Veenstra, B. A. Lipsky, S. Saint, Use of Maximal Sterile Barriers during Central Venous Catheter Insertion: Clinical and Economic Outcomes Clinical Infectious Diseases. ,vol. 39, pp. 1441- 1445 ,(2004) , 10.1086/425309
Marie-Christine Herrault, Carole Schwebel, Stéphane Ruckly, Bertrand Souweine, Jean-Christophe Lucet, Jean-François Timsit, Lila Bouadma, Olivier Mimoz, Jean-Jacques Parienti, Maïté Garrouste-Orgeas, Serge Alfandari, Gaétan Plantefeve, Régis Bronchard, Gilles Troche, Remy Gauzit, Marion Antona, Emmanuel Canet, Julien Bohe, Jugular Versus Femoral Short-Term Catheterization and Risk of Infection in Intensive Care Unit Patients. Causal Analysis of Two Randomized Trials American Journal of Respiratory and Critical Care Medicine. ,vol. 188, pp. 1232- 1239 ,(2013) , 10.1164/RCCM.201303-0460OC
Dennis R. Schaberg, David H. Culver, Robert P. Gaynes, Major trends in the microbial etiology of nosocomial infection The American Journal of Medicine. ,vol. 91, pp. 72- 75 ,(1991) , 10.1016/0002-9343(91)90346-Y