作者: N. J. M. Birdsall
DOI: 10.1007/978-1-4684-1140-9_18
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摘要: With the development of receptor-specific ligands, radiolabelled to high specific activity, it has become feasible study directly binding drugs their receptors. This approach can be used measure detailed properties receptors in whole tissue as well membrane preparations. In particular is possible determine both number and localisation receptor sites nervous system. These results complement information regarding distribution assessed by electrophysiological other histochemical techniques. The muscarinic acetylcholine one example which biochemical approaches are being further characterise a neurotransmitter