Effects of tissue-tolerable plasma on psoriasis vulgaris treatment compared to conventional local treatment: A pilot study

作者: M. Klebes , J. Lademann , S. Philipp , C. Ulrich , A. Patzelt

DOI: 10.1016/J.CPME.2013.11.002

关键词:

摘要: Abstract The effect of tissue-tolerable plasma (TTP) on inflammatory diseases such as psoriasis was investigated. Three plaques six psoriatic patients were subjected to different treatments (A: TTP, brine baths (BB)+5% salicylic acid ointment (SAO); B: BB+SAO; C: BB, UV irradiation, SAO+dithranol). While redness and infiltration reduced in groups A C, scaling group C. TTP temporarily the bacterial colonization skin lesions. In summary, treatment with showed no significant advantage over conventional therapies.

参考文章(38)
Ge Zhao, Marcia L. Usui, Robert A. Underwood, Pradeep K. Singh, Garth A. James, Philip S. Stewart, Philip Fleckman, John E. Olerud, Time course study of delayed wound healing in a biofilm-challenged diabetic mouse model. Wound Repair and Regeneration. ,vol. 20, pp. 342- 352 ,(2012) , 10.1111/J.1524-475X.2012.00793.X
Kevin J. Trouba, Hisham K. Hamadeh, Rupesh P. Amin, Dori R. Germolec, Oxidative Stress and Its Role in Skin Disease Antioxidants & Redox Signaling. ,vol. 4, pp. 665- 673 ,(2002) , 10.1089/15230860260220175
G. Isbary, J. Heinlin, T. Shimizu, J.L. Zimmermann, G. Morfill, H.-U. Schmidt, R. Monetti, B. Steffes, W. Bunk, Y. Li, T. Klaempfl, S. Karrer, M. Landthaler, W. Stolz, Successful and safe use of 2 min cold atmospheric argon plasma in chronic wounds: results of a randomized controlled trial. British Journal of Dermatology. ,vol. 167, pp. 404- 410 ,(2012) , 10.1111/J.1365-2133.2012.10923.X
J Heinlin, G Isbary, W Stolz, G Morfill, M Landthaler, T Shimizu, B Steffes, T Nosenko, JL Zimmermann, S Karrer, Plasma applications in medicine with a special focus on dermatology Journal of The European Academy of Dermatology and Venereology. ,vol. 25, pp. 1- 11 ,(2011) , 10.1111/J.1468-3083.2010.03702.X
Aaron M. Drucker, Akerke Baibergenova, Cheryl F. Rosen, Neil H. Shear, Narrowband UVB as an effective substitute for psoralen plus UVA: lessons from a psoralen shortage Photodermatology, Photoimmunology and Photomedicine. ,vol. 28, pp. 267- 268 ,(2012) , 10.1111/J.1600-0781.2012.00683.X
B. Lange-Asschenfeldt, D. Marenbach, C. Lang, A. Patzelt, M. Ulrich, A. Maltusch, D. Terhorst, E. Stockfleth, W. Sterry, J. Lademann, Distribution of Bacteria in the Epidermal Layers and Hair Follicles of the Human Skin Skin Pharmacology and Physiology. ,vol. 24, pp. 305- 311 ,(2011) , 10.1159/000328728
A. Hammann, N.-O. Huebner, C. Bender, A. Ekkernkamp, B. Hartmann, P. Hinz, E. Kindel, I. Koban, S. Koch, T. Kohlmann, J. Lademann, R. Matthes, G. Müller, R. Titze, K.-D. Weltmann, A. Kramer, Antiseptic Efficacy and Tolerance of Tissue-Tolerable Plasma Compared with Two Wound Antiseptics on Artificially Bacterially Contaminated Eyes from Commercially Slaughtered Pigs Skin Pharmacology and Physiology. ,vol. 23, pp. 328- 332 ,(2010) , 10.1159/000314724
N.-O. Hübner, R. Matthes, I. Koban, C. Rändler, G. Müller, C. Bender, E. Kindel, T. Kocher, A. Kramer, Efficacy of chlorhexidine, polihexanide and tissue-tolerable plasma against Pseudomonas aeruginosa biofilms grown on polystyrene and silicone materials. Skin Pharmacology and Physiology. ,vol. 23, pp. 28- 34 ,(2010) , 10.1159/000318265
Juergen Lademann, Heike Richter, Alena Alborova, Daniel Humme, Alexa Patzelt, Axel Kramer, Klaus-Dieter Weltmann, Bernd Hartmann, Christian Ottomann, Joachim W. Fluhr, Peter Hinz, Georg Hübner, Olaf Lademann, Risk assessment of the application of a plasma jet in dermatology. Journal of Biomedical Optics. ,vol. 14, pp. 054025- 054025 ,(2009) , 10.1117/1.3247156