"The Acth Axis: Pathogenesis, Diagnosis and Treatment"
作者： Rolf C. Gaillard
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摘要: 1. Ontogeny of the pituitary corticotroph system.- 2. Proopiomelanocortin gene expression in man.- 3. Multifactorial regulation axis: animal models.- 4. CRH-receptors and their ligands.- 5. ACTH precursors different pathological conditions.- 6. Interactions between hypothalamo-pituitary-adrenal axis immunological 7. Pituitary SOCS-3: an important regulator POMC expression.- 8. The melanocortin pathway food intake.- 9. receptor its mutations.- 10. Leptin axis.- 11. Cushing's syndrome due to aberrant adrenal hormone receptors.- 12. Cushing' s - diagnosis diffrential diagnosis.- 13. Lost found: pars intermedia human role histogenesis silent "corticotroph" adenomas.- 14. Therapeutic strategies disease.- 15. Syndromes glucocorticoid resistance.
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springer.com 参考文章(270)
C.W. Burke, Adrenocortical insufficiency Clinics in Endocrinology and Metabolism. ,vol. 14, pp. 947- 976 ,(1985) , 10.1016/S0300-595X(85)80084-0
Chrousos Gp, Nieman Lk, Doherty Gm, Cutler Gb, Norton Ja, Time to recovery of the hypothalamic-pituitary-adrenal axis after curative resection of adrenal tumors in patients with Cushing's syndrome. Surgery. ,vol. 108, pp. 1085- 1090 ,(1990)
François Pierre Pralong, Rolf Christian Gaillard, Neuroendocrine effects of leptin. Pituitary. ,vol. 4, pp. 25- 32 ,(2001) , 10.1023/A:1012930609563
H. König, H. Ponta, H.J. Rahmsdorf, P. Herrlich, Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo. The EMBO Journal. ,vol. 11, pp. 2241- 2246 ,(1992) , 10.1002/J.1460-2075.1992.TB05283.X
Robert A. Kesterson, Roger D. Cone, Bruce Boston, Sandhya Koppula, Dag Inge Vage, David N. Orth, Dongsi Lu, Wenbiao Chen, Colin Pouton, Helge Klungland, The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation Recent Progress in Hormone Research. ,vol. 51, pp. 287- 317 ,(1996)
C V Rao, The beginning of a new era in reproductive biology and medicine: Expression of low levels of functional luteinizing hormone human chorionic gonadotropin receptors in nongonadal tissues Journal of Physiology and Pharmacology. Supplement. ,vol. 47, ,(1996)
Donald J. Marsh, Gunther Hollopeter, Dennis Huszar, Ralph Laufer, Keith A. Yagaloff, Stewart L. Fisher, Paul Burn, Richard D. Palmiter, Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides. Nature Genetics. ,vol. 21, pp. 119- 122 ,(1999) , 10.1038/5070
S P Smeekens, D F Steiner, Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2. Journal of Biological Chemistry. ,vol. 265, pp. 2997- 3000 ,(1990) , 10.1016/S0021-9258(19)39721-2
Michael A. Cowley, James L. Smart, Marcelo Rubinstein, Marcelo G. Cerdán, Sabrina Diano, Tamas L. Horvath, Roger D. Cone, Malcolm J. Low, Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus Nature. ,vol. 411, pp. 480- 484 ,(2001) , 10.1038/35078085
Carl T. Montague, I. Sadaf Farooqi, Jonathan P. Whitehead, Maria A. Soos, Harald Rau, Nicholas J. Wareham, Ciaran P. Sewter, Janet E. Digby, Shehla N. Mohammed, Jane A. Hurst, Christopher H. Cheetham#, Alison R. Earley#, Anthony H. Barnett, Johannes B. Prins, Stephen O'Rahilly, Congenital leptin deficiency is associated with severe early-onset obesity in humans Nature. ,vol. 387, pp. 903- 908 ,(1997) , 10.1038/43185