Improved physiological properties of gravity‐enforced reassembled rat and human pancreatic pseudo‐islets
作者： R. A. Zuellig , G. Cavallari , P. Gerber , O. Tschopp , G. A. Spinas
DOI: 10.1002/TERM.1891
关键词:
摘要: Previously we demonstrated the superiority of small islets vs large islets in terms of function and survival after transplantation, and we generated reaggregated rat islets (pseudo‐islets) of standardized small dimensions by the hanging‐drop culture method (HDCM). The aim of this study was to generate human pseudo‐islets by HDCM and to evaluate and compare the physiological properties of rat and human pseudo‐islets. Isolated rat and human islets were dissociated into single cells and incubated for 6–14 days by HDCM. Newly formed pseudo …
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