A sensitive and reproducible method for the assay of human islet cell antibodies.
作者： C.C. Pilcher , R.B. Elliott
DOI: 10.1016/0022-1759(90)90427-W
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摘要: Abstract The islet cell antibody test is increasingly used to predict insulin-dependent diabetes before it clinically apparent. Four international workshops on the have shown wide variations in reproducibility, sensitivity and specificity. This illustrates need for a more clearly defined method. We report technique which offers both increased reproducibility. Using this method 94% of newly diagnosed diabetic children ICA levels ⩾ 10 units, whereas only 1.5% normal are positive at his level, 7% first degree relatives (aged less then 20 years) IDDM patients.
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