Coexistence of aortic valve stenosis and cardiac amyloidosis: echocardiographic and clinical significance

摘要: Left ventricular hypertrophy and diastolic dysfunction are common echocardiographic features of both aortic valve stenosis (AS) cardiac amyloidosis (CA). These two different entities therefore may mask each other. From recent years, there is a growing body evidence about the relatively high incidence wild-type transthyretin (wtTTR) in AS, but scarce data on prevalence AS CA, particularly AL-type amyloidosis. The approach to these patients not obvious, based. We aimed study prevalence, severity, type with CA also evaluate potential echocardiography diagnostic process. Between January 2009 2019, we retrospectively analyzed clinical data, work up 55 consecutive patients. 80% our had AL identified 5 (9%) moderate severe AS: three low-flow, low-grade (LFLG AS). Further analysis latter dobutamine stress revealed pseudo-severe LFLG two, true-severe one patient. 9% population patients, majority whom have Dobutamine seems be appropriate for further characterization even normal ejection fraction.