Molecular marker for mitosis

作者: C. David Allis , Kevin F. Sullivan

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摘要: The present invention relates to modified peptide sequences that serve as unique molecular markers of cell division. More particularly the is directed amino terminus a histone H3-like protein, CENP-A, and antibodies bind this peptide. Only cells are dividing phosphorylated at Ser7 (see Fig. 2C) an antibody specific for peptides can be used identify such cells.

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