Pulsed-dye laser versus conventional therapy in the treatment of warts: A prospective randomized trial

摘要: Abstract Background: The clinical management of verrucae vulgaris is often challenging, and no ideal treatment currently exists. Early studies suggested that pulsed-dye laser (PDL) therapy might be highly effective in the verrucae, although more recent reports have been less optimistic. Previous retrospective or consisted a series patients treated with PDL alone. Objective: Our objective was to prospectively evaluate efficacy versus conventional liquid nitrogen cryotherapy cantharidin warts. Methods: Forty healthy adult were randomized receive either (585 nm) therapy. All enrollees also performed home Patients eligible for up 4 sessions at 1-month intervals. Warts individually counted measured time each session. Complete response defined as complete absence presence dermatoglyphics, partial 50% greater reduction wart size. Results: A total 194 warts evaluated by conclusion study. noted an average 70% 66% those group; this statistically insignificant. Partial observed 82% 87% group. Verruca responded readily than verruca plantaris both groups. mean number treatments achieve success similar Conclusion: efficacious form should considered among better established approaches warts, data from trial suggest approach probably not superior. (J Am Acad Dermatol 2000;43:275-80.)