Genetics of bacterial alginate: alginate genes distribution, organization and biosynthesis in bacteria.

摘要: Bacterial alginate genes are chromosomal and fairly widespread among rRNA homology group I Pseudomonads Azotobacter. In both genera, the genetic pathway of biosynthesis is mostly similar identified identically organized into biosynthetic, regulatory switching clusters. spite these similarities,still there transcriptional functional variations between P. aeruginosa A. vinelandii. all biosynthetic except algC transcribe in polycistronic manner under control algD promoter while vinelandii, many units. Of these, algA transcribed each from two different three promoters. Unlike aeruginosa, promoters units one algT-independent. Both bacterial species carry homologous algG gene for Ca2+-independent epimerization. But besides algG, vinelandii also has algE1-7 which encode C-5-epimerases involved complex steps Ca2+-dependent A hierarchy expression σ22(algT) exists where algT required transcription response regulators algB algR, turn necessary its downstream genes. Although algTmucABCD cluster play roles but unlike, algR independent σ22. These differences could be due to fact that plays a role as an integrated part desiccation-resistant cyst not found aeruginosa.