作者: David James Peter Henderson , Ralf Hoffmann , Miles Douglas Houslay
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摘要: The present invention relates to phosphodiesterase 4D7 (PDE4D7) for use as a marker prostate cancer, and the of PDE4D7 diagnosing, detecting, monitoring or prognosticating cancer progression cancer. also composition corresponding method immunoassay, hormone-resistant vs. hormone-sensitive data acquisition, an immunoassay identifying individual eligibility therapy, stratifying cohort individuals with disease, well pharmaceutical comprising compound directly stimulating modulating activity PDE4D7, indirectly protein biologically active equivalent thereof, nucleic acid encoding expressing miRNA inhibitor specific miRNAs, demethylation agent and/or displacement factor.