Methods of prostate cancer prognosis

作者: Ralf Hoffmann , Márcia Alves De Inda , Anne Godefrida Catharina Van Brussel , Janneke Wrobel , Dianne Arnoldina Margaretha Wilhelmina Van Strijp

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摘要: The present invention pertains to methods for determining gene expression signatures diagnosing patients with prostate cancer, e.g., establish a prognosis such patients, the predisposition of said patient develop aggressive or indolent disease, example after primary treatment, and/or identification and stratification available therapies. also relates products used in methods, e.g. kits, software, like. further therapies use treatment that have been diagnosed, identified, stratified any disclosed herein.

参考文章(22)
Eric Paquet, Yves Fradet, Guillaume Beaudry, Jean-Francois Haince, Methods, kits and compositions for providing a clinical assessment of prostate cancer ,(2013)
Joost L. Boormans, Hanneke Korsten, Angelique J.C. Ziel-van der Made, Geert J.L.H. van Leenders, Carola V. de Vos, Guido Jenster, Jan Trapman, Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer. International Journal of Cancer. ,vol. 133, pp. 335- 345 ,(2013) , 10.1002/IJC.28025
Jo Vandesompele, Katleen De Preter, Filip Pattyn, Bruce Poppe, Nadine Van Roy, Anne De Paepe, Frank Speleman, Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biology. ,vol. 3, pp. 1- 12 ,(2002) , 10.1186/GB-2002-3-7-RESEARCH0034
Virginie Durbecq, Martine Piccart, Christos Sotiriou, Mauro Delorenzi, Gene-based algorithmic cancer prognosis ,(2006)
David James Peter Henderson, Ralf Hoffmann, Miles Douglas Houslay, Phosphodiesterase 4d7 as marker for malignant, hormone-sensitive prostate cancer ,(2010)
David James Peter Henderson, Ralf Hoffmann, Miles Douglas Houslay, Phosphodiesterase 4D7 as prostate cancer marker ,(2010)
Rei Mimoto, Naoe Taira, Hiroyuki Takahashi, Tomoko Yamaguchi, Masataka Okabe, Ken Uchida, Yoshio Miki, Kiyotsugu Yoshida, DYRK2 controls the epithelial–mesenchymal transition in breast cancer by degrading Snail Cancer Letters. ,vol. 339, pp. 214- 225 ,(2013) , 10.1016/J.CANLET.2013.06.005
Nicholas Erho, Anamaria Crisan, Ismael A. Vergara, Anirban P. Mitra, Mercedeh Ghadessi, Christine Buerki, Eric J. Bergstralh, Thomas Kollmeyer, Stephanie Fink, Zaid Haddad, Benedikt Zimmermann, Thomas Sierocinski, Karla V. Ballman, Timothy J. Triche, Peter C. Black, R. Jeffrey Karnes, George Klee, Elai Davicioni, Robert B. Jenkins, Discovery and Validation of a Prostate Cancer Genomic Classifier that Predicts Early Metastasis Following Radical Prostatectomy PLoS ONE. ,vol. 8, pp. e66855- ,(2013) , 10.1371/JOURNAL.PONE.0066855