Preoperative assessment of chest wall invasion in non-small cell lung cancer using surgeon-performed ultrasound.

摘要: Background Chest wall invasion in operable lung cancer upgrades the stage and can affect operative planning. Diagnosing chest preoperatively is important patient consent, choice of incision placement, be helpful choosing an approach (open vs thoracoscopic). The objectives this study were to determine diagnostic accuracy preoperative, surgeon-performed ultrasound (US) assessing tumoral (T3) non-small cell (NSCLC) patients compare its preoperative computed tomography (CT). Methods This was a prospective clinical trial (ClinicalTrials.gov: NCT01206894) that prospectively enrolled between September 2010 January 2013. Eligible included those with NSCLC abutting parietal pleura or invading on CT scan who planned for surgical resection. Criteria US (1) disruption pleura, (2) ribs, (3) impairment pleural movement respiration. examination performed by thoracic team immediately before intervention. Sensitivity specificity calculated using definitive final pathologic analysis as gold standard invasion. Results During 28-month period, 28 (15 men 13 women) enrolled. Mean age 62 ± 11 years, mean body mass index 25.3 4.5 kg/m 2 . average time assessment looking 5.3 5 minutes. sensitivity evaluating 90.9% 85.7%. associated 61.5% 84.6%. positive negative predictive values 83.3% 92.3%, respectively, compared 80% 68.8% scan. Conclusions Surgeon-performed reliably diagnose NSCLC. has poor predicting preoperatively. considered complementary adjunct imaging pulmonary lesions improve diagnosis, staging,