Moonlighting activity of the epigenetic machinery restrains infection
作者： Claude Gutierrez , Yves‐Marie Boudehen , Olivier Neyrolles
关键词:
摘要: Intracellular bacterial pathogens have evolved a range of mechanisms, including manipulation the host cell epigenetic machinery and gene expression rewiring, to parasitize thrive inside phagocytes. A new study in The EMBO Journal (Yaseen et al , 2017) reports that, conversely, macrophages can use modulators modify surface invading counteract infection. This opens avenues better understand host–pathogen interactions develop novel, more effective antimicrobial strategies.
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