Therapeutic combination of amlodipine and benazepril/benazeprilat

作者: Alan Edward Royce , William Lionel Daley , Ann Reese Comfort , Randy Lee Webb , William Shifeng Wei

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摘要: The present invention especially relates to the use of a combination comprising (1) an ACEI selected from group consisting benazepril, benazeprilat, and pharmaceuticall acceptable salts thereof, (2) amlodipine or pharmaceutically salt for manufacture medicament treatment prevention delay progression condition hypertension, congestive heart failure, angina, myocardial infarction, artherosclerosis, diabetic nephropathy, cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, blood pressure-related cerebrovasular stroke, pulmonary disease hypertension headache; wherein (i) amount thereof corresponds 6 about mg 40 free base (ii) ACE inhibitor 20 160 benazepril hydrochloride.

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