Salivary glands in ixodid ticks: control and mechanism of secretion
作者： J.R Sauer , R.C Essenberg , A.S Bowman
DOI: 10.1016/S0022-1910(99)00210-3
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摘要: Abstract The salivary glands are vital to the biological success of ixodid ticks and major route for pathogen transmission. Important functions include absorption water vapor from unsaturated air by free-living ticks, excretion excess fluid blood meal concentration, secretion bioactive protein lipid compounds during tick feeding. Fluid is controlled nerves. Dopamine neurotransmitter at neuroeffector junction regulating via adenylate cyclase an increase in cellular cAMP. also affects release arachidonic acid which subsequently converted prostaglandins. Prostaglandin E2 (PGE2) secreted extremely high levels into saliva export host where it impacts physiology. Additionally, PGE2 has autocrine or paracrine role within gland itself interacts with a receptor induce (exocytosis) proteins phosphoinositide signalling pathway Ca2+. Regulation been extensively studied, but little known about mechanism secretion. Continuing advances physiology will be made as key regulatory secretory purified and/or their genes cloned sequenced.
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A. van de Locht, M. T. Stubbs, W. Bode, T. Friedrich, C. Bollschweiler, W. Höffken, R. Huber, The ornithodorin-thrombin crystal structure, a key to the TAP enigma? The EMBO Journal. ,vol. 15, pp. 6011- 6017 ,(1996) , 10.1002/J.1460-2075.1996.TB00989.X
John R. Sauer, J. Alexander Hair, Morphology, physiology, and behavioral biology of ticks E. Horwood , Halsted Press. ,(1986)
S Wiemann, V Kinzel, W Pyerin, Isoform C beta 2, an unusual form of the bovine catalytic subunit of cAMP-dependent protein kinase. Journal of Biological Chemistry. ,vol. 266, pp. 5140- 5146 ,(1991) , 10.1016/S0021-9258(19)67766-5
J. Karczewski, R. Endris, T.M. Connolly, Disagregin is a fibrinogen receptor antagonist lacking the Arg-Gly-Asp sequence from the tick, Ornithodoros moubata. Journal of Biological Chemistry. ,vol. 269, pp. 6702- 6708 ,(1994) , 10.1016/S0021-9258(17)37432-X
P.M. Keller, L. Waxman, B.A. Arnold, L.D. Schultz, C. Condra, T.M. Connolly, Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation. Journal of Biological Chemistry. ,vol. 268, pp. 5450- 5456 ,(1993) , 10.1016/S0021-9258(18)53342-1
K.C. Binnington, D.H. Kemp, Role of Tick Salivary Glands in Feeding and Disease Transmission Advances in Parasitology. ,vol. 18, pp. 315- 339 ,(1980) , 10.1016/S0065-308X(08)60403-0
M D Uhler, J C Chrivia, G S McKnight, Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase. Journal of Biological Chemistry. ,vol. 261, pp. 15360- 15363 ,(1986) , 10.1016/S0021-9258(18)66717-1
Andrea L. Crampton, Catherine Miller, Glenn D. Baxter, Stephen C. Barker, Expressed sequenced tags and new genes from the cattle tick, Boophilus microplus. Experimental and Applied Acarology. ,vol. 22, pp. 177- 186 ,(1998) , 10.1023/A:1006058113409
Hui Wang, Guido C. Paesen, Patricia A. Nuttall, Alan G. Barbour, Male ticks help their mates to feed Nature. ,vol. 391, pp. 753- 754 ,(1998) , 10.1038/35773
W Knülle, K Gaede, On the mechanism of water vapour sorption from unsaturated atmospheres by ticks The Journal of Experimental Biology. ,vol. 200, pp. 1491- 1498 ,(1997) , 10.1242/JEB.200.10.1491