Idiopathic Ventricular Tachycardia. Epidemiology, Pathophysiology, Primary Prevention, Immediate Evaluation and Management, Long-term Management, Experimental and Theoretical Developments

摘要: Classi~cation schemes for idiopathic VT vary, but the most commonly used scheme divides these arrhythmias into: (1) repetitive monomorphic VT; (2) paroxysmal sustained and (3) left VT. Idiopathic is also referred to as verapamil-sensitive Paroxysmal often called catecholamine-responsive or exercise-induced Over past year two, relatively little has been published alter classi~cation Lerman et al.1 have investigated mechanism of using adenosine, vagal maneuvers, edrophonium, beta blockade calcium channel blockade. They concluded that was probably due cyclic AMP-mediated triggered activity, similar Two articles appeared describing polymorphic in patients with a normal QT.2,3 Eisenberg al.3 found their could be divided into three distinct groups. One group had induced by exercise initiated late-coupled beats. All four responded Another during episodes coronary spasm Polymorphic unrelated exertion occurred third group. Tachycardia began closely coupled beats pause many patients. Sudden death prevalent This described Leenhardt thought variant adrenergic-dependent long QT syndrome. Pathopysiology