Primary prevention of CVD: diet and weight loss

摘要: Introduction Diet is an important cause of many chronic diseases. Individual change in behaviour has the potential to decrease burden disease, particularly cardiovascular disease (CVD). Methods and objectives We conducted a systematic review aimed answer following clinical questions: What are effects interventions general population reduce sodium intake? cholesterol-lowering diet population? increase or maintain weight loss? eating more fruit vegetables on reducing CVD risk antioxidants omega 3 fatty acids reduction Mediterranean searched: Medline, Embase, The Cochrane Library other databases up August 2006 (BMJ Clinical Evidence reviews updated periodically, please check our website for most up-to-date version this review). included harms alerts from relevant organisations such as US Food Drug Administration (FDA) UK Medicines Healthcare products Regulatory Agency (MHRA). Results found 47 reviews, RCTs, observational studies that met inclusion criteria. performed GRADE evaluation quality evidence interventions. Conclusions In we present information relating effectiveness safety interventions: advice intake, saturated fat behavioural counselling interventions, diets lose weight, high-dose antioxidant supplements, vegetable lifestyle diet, acids, training health professionals promoting loss.