Treatment of erythrasma: A double-blinded randomized controlled trial on the clinical application of clotrimazole and sertaconazole

摘要: Introduction: Topical clotrimazole and sertaconazole may be effective in the treatment of erythrasma, a superficial skin infection developed by group aerobic microorganisms. This study aimed to compare effect on erythrasma. Methods: In this double-blinded randomized controlled trial, 40 age-matched patients with confirmed erythrasma diagnosis were divided into two equal groups; one treated topical 2% other 1% clotrimazole. The clinical features monitored for weeks (baseline, day 7, 14) compared. Data analyzed using SPSS v16 software. Results: On group, reduction erythema pigmentation more prominent comparison (P=0.02 P=0.005, respectively), but there was no difference considering scaling between groups. 14, terms reduction, performed better compared (P=0.04). Both groups had significant symptoms during their period (P<0.001). Conclusions: Regarding results, both are medications treatment. Still, has faster recovery process sertaconazole, is observed outcomes after