作者: Rinaldo Bellomo , Paul M. Palevsky , Sean M. Bagshaw , Noel Gibney , Finlay A. McAlister
DOI: 10.1159/000313770
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摘要: Several large observational studies or randomized controlled trials in the field of critical care nephrology have been completed and reported, recently begun recruitment. These provide important information to guide our appreciation current practice consider new potentially effective intervention for prevention attenuation acute kidney injury suggest avenues use renal replacement therapy (RRT) treatment sepsis. In particular, two studies, ATN study RENAL (both multicenter > 1,000 patients) provide, first time, level I evidence RRT critically ill patients better define optimal intensity such this setting. Clinicians practicing need be aware these trials, their details, findings design recruitment rate likely time completion continue offer highest evidence-based medical care.