Depletion by capsaicin of substance P-immunoreactivity and acetylcholinesterase activity from nerve fibres in the guinea-pig heart.

作者: R.E. Papka , J.B. Furness , N.G. Della , M. Costa

DOI: 10.1016/0304-3940(81)90204-4

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摘要: The sensitivity to capsaicin of substance P-immunoreactive nerve fibres in the hearts guinea-pigs was examined. Capsaicin decreased considerably material parietal pericardium, atria, bicuspid and tricuspid valves. Pericardial valvar localized by acetylcholinesterase (AChE) histochemistry had a distribution density pattern similar that P immunoreactive fibres. treatment also number visible AChE-positive It is known has selective action on those are sensory origin; thus, these results imply heart sensory. Moreover, suggest some AChE P-containing

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