Polycomb complexes and silencing mechanisms
作者： Anders H Lund , Maarten van Lohuizen
DOI: 10.1016/J.CEB.2004.03.010
关键词:
摘要: Advances in the past couple of years have brought important new knowledge on mechanisms by which Polycomb-group proteins regulate gene expression and consequences their actions. The discovery histone methylation imprints specific for Polycomb Trithorax complexes has provided mechanistic insight how this ancient epigenetic memory system acts to repress indicates that it may share aspects with other silencing genome-protective processes, such as RNA interference.
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