Immunohistochemical staining of Langerhans cells and macrophages in oral lichen planus
作者： Joseph A. Regezi , Jeffery C.B. Stewart , Ricardo V. Lloyd , John T. Headington
DOI: 10.1016/0030-4220(85)90262-2
关键词:
摘要: Twenty patients with clinically and microscopically confirmed lichen planus were studied immunohistochemically. Monoclonal antibody to HLA-DR antigens polyclonal antisera S-100 protein muramidase applied paraffin-embedded sections for the purpose of elaborating on pathogenesis this disease. Trypsin incubation was also done in order determine its effect immunostaining. Langerhans cells identified anti-S-100 anti-HLA-DR, macrophages antimuramidase anti-HLA-DR. Keratinocytes expressed membrane activity tissue. Trypsinization significantly improved expression antigens. It concluded that cells, macrophages, keratinocytes play important roles antigen processing and/or phagocytosis during natural history
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