A rare case of Merkel cell carcinoma presenting as a giant intra-thoracic mass: A case report and review of the literature.

摘要: Rationale Merkel cell carcinoma (MCC) is an aggressive neuroendocrine-derived cutaneous cancer. Ectopic or single metastatic MCC located in thorax extremely rare; meanwhile, its definite management has not been elucidated yet. Patient concerns A 64-year-old female patient with a giant mass her left was presented for stuffy pain of chest 6 months and fever half month. She underwent radical resection vulvar 10 years ago. Diagnoses Computed tomography (CT)-guided biopsy the intrathoracic revealed diagnosis MCC, without synchronous urogenital lesions on pelvic CT images. Interventions This bulky tumor completely resected via thoracotomy, along adjacent pulmonary lobe, pericardium, pleura, diaphragm. Outcomes The survived local-regional recurrence distant metastasis during follow-up 1 year up to now. Lessons should be considered differential tumors, especially patients history MCC. Besides, timely surgery combined chemotherapy effective this disease.