Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission
作者： Stefanie Sowinski , Clare Jolly , Otto Berninghausen , Marco A. Purbhoo , Anne Chauveau
DOI: 10.1038/NCB1682
关键词:
摘要: , as a dynamic junction persists within T-cell nanotubes or at their contact with cell bodies. We also report that an extracellular matrix scaffold allows to adopt variably shaped contours. HIV-1 transfers uninfected T cells through in receptor-dependent manner. These data lead us propose can spread using nanotubular connections formed by short-term intercellular unions which specialize.
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