Spaceflight Induced Disorders: Potential Nutritional Countermeasures.

作者: Fabio Costa , Francesco Saverio Ambesi-Impiombato , Tommaso Beccari , Carmela Conte , Samuela Cataldi

DOI: 10.3389/FBIOE.2021.666683

关键词:

摘要: Space travel is an extreme experience even for the astronaut who has received extensive basic training in various fields, from aeronautics to engineering, medicine physics and biology. Microgravity puts a strain on members of space crews, both physically mentally: short-term or long-term orbit International Station may have serious repercussions human body, which undergo physiological changes affecting almost all organs systems, particularly at muscular, cardiovascular bone compartments. This review aims highlight recent studies describing damages body induced by environment microgravity, radiation. All novel conditions, ally unknown Darwinian selection strategies Earth, we should add psychological stress that astronauts suffer due inevitable forced cohabitation claustrophobic environments, deprivation their affections need adapt new lifestyle with molecular confinement. In this context, significant nutritional deficiencies consequent mechanism cells induce onset cognitive impairment been considered.

参考文章(62)
L. N. Kornilova, I. B. Kozlovskaya, Neurosensory mechanisms of space adaptation syndrome Fiziologiia cheloveka. ,vol. 29, pp. 17- 28 ,(2003) , 10.1023/A:1025899413655
Monica S Da Silva, Pamela M Zimmerman, Michael M Meguid, Jyotirmoy Nandi, Kosaku Ohinata, Yuan Xu, Chung Chen, Tomoko Tada, Akio Inui, Anorexia in space and possible etiologies ☆: An overview Nutrition. ,vol. 18, pp. 805- 813 ,(2002) , 10.1016/S0899-9007(02)00915-2
T. P. Stein, M. J. Leskiw, Oxidant damage during and after spaceflight American Journal of Physiology-endocrinology and Metabolism. ,vol. 278, ,(2000) , 10.1152/AJPENDO.2000.278.3.E375
Scott M. Smith, Sara R. Zwart, Gladys Block, Barbara L. Rice, Janis E. Davis-Street, The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station Journal of Nutrition. ,vol. 135, pp. 437- 443 ,(2005) , 10.1093/JN/135.3.437
Elisabetta Albi, Francesco Curcio, Andrea Lazzarini, Alessandro Floridi, Samuela Cataldi, Remo Lazzarini, Elisabetta Loreti, Ivana Ferri, Francesco Saverio Ambesi-Impiombato, How Microgravity Changes Galectin-3 in Thyroid Follicles BioMed Research International. ,vol. 2014, pp. 652863- 652863 ,(2014) , 10.1155/2014/652863
G Sonnenfeld, None, Animal models for the study of the effects of spaceflight on the immune system Advances in Space Research. ,vol. 32, pp. 1473- 1476 ,(2003) , 10.1016/S0273-1177(03)90383-8
Jennifer M. Sacheck, Jeffrey B. Blumberg, Role of vitamin E and oxidative stress in exercise. Nutrition. ,vol. 17, pp. 809- 814 ,(2001) , 10.1016/S0899-9007(01)00639-6
Maddalena Mognato, Cristina Girardi, Sonia Fabris, Lucia Celotti, DNA repair in modeled microgravity: Double strand break rejoining activity in human lymphocytes irradiated with γ-rays Mutation Research. ,vol. 663, pp. 32- 39 ,(2009) , 10.1016/J.MRFMMM.2009.01.002
T. P. Stein, Weight, muscle and bone loss during space flight: another perspective European Journal of Applied Physiology. ,vol. 113, pp. 2171- 2181 ,(2013) , 10.1007/S00421-012-2548-9
T Peter Stein, Stéphane Blanc, None, Does protein supplementation prevent muscle disuse atrophy and loss of strength Critical Reviews in Food Science and Nutrition. ,vol. 51, pp. 828- 834 ,(2011) , 10.1080/10408398.2010.482679