Assessment of the Efficacious Dose of Arachidonic and Docosahexaenoic Acids in Preterm Infant Formulas: Fatty Acid Composition of Erythrocyte Membrane Lipids
作者： M T Clandinin , J E Van Aerde , A Parrott , C J Field , A R Euler
DOI: 10.1203/00006450-199712000-00017
关键词:
摘要: The nutritional requirements of preterm infants for the long chain polyunsaturated essential fatty acids, arachidonic acid (AA) and docosahexaenoic (DHA), have not been clearly defined. present study evaluated less than 2.3 kg birth weight fed a commercial formula (Preemie SMA®) devoid AA DHA compared this control group with similar infant groups one three formulas containing range 0.32 to 1.1% 0.24 0.76% DHA. An analogous their mothers' breast milk fortifier (when indicated) was also studied. Erythrocyte membrane phospholipids were isolated from blood samples collected at 12 d age after further 4 wk feeding. Infants without showed reduction in level erythrocyte phosphatidylcholine, reduced phosphatidylethanolamine comparison or Supplementing increasing levels produced clear dose response found phospholipids. From phospholipid composition it appears that 0.32-1.1% 0.24-0.76% provides sufficient these acids achieve human most lipid fractions examined.
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