Megalencephalic leukoencephalopathy with subcortical cysts: A report of four cases.

摘要: Megalencephalic leukoencephalopathy with subcortical cysts is an inherited autosomal recessive disorder characteristic MRI features and a variable but mild clinical course. Frontal temporal are the diagnostic hallmark. It usually presents pyramidal cerebellar signs. Megalencephaly detected early. Seizures may be present easily controlled. has been reported commonly from certain ethnicity of northern Indian origin, its presence global. We encountered four patients describe radiological these patients. though to uncommon were seen in all our Neuropsychiatric have not described as presentation so far one had moderately severe depression. All diagnosed by they responded well symptomatic treatment.