Sporozoite and liver-stage protein antigen of P. falciparum

摘要: The invention relates to a polypeptide characterized in that it comprises at least one peptide sequence carrying or more epitopes characteristic of protein produced the sporozoite stage and hepatocytes infected with P. falciparum, this comprising succession 10 amino acids maximum number following sequence: Glu-Phe-Arg-Val-Ser-Thr-Ser-Asp-Thr-Pro-Gly-Gly-Asn-Glu-Ser-Ser -Ser-Ala-Phe-Pro-Gln-Phe-Ile-Trp-Ser-Ala-Glu-Lys-Lys-Asp-Glu-Lys-Glu-Ala-Ser-Glu-Gln-Gly-Glu-Glu-Ser -His-Lys-Lys-Glu-Asn-Ser-Gln-Glu-Ser-Ala-Asn-Gly-Lys-Asp-Asp-Val-Lys-Glu-Glu-Lys-Lys-Thr-Asn-Glu-Lys -Lys-Asp-Asp-Gly-Lys-Thr-Asp-Lys-Val-Gln-Glu-Lys-Val-Leu-Glu-Lys-Ser-Pro-Lys-Glu-Phe. It also use these polypeptides, as well nucleotide sequences coding for methods vitro diagnosis malaria on biological sample originating from individual whom disease is be screened.