Process and intermediates for the preparation of halogenated protease inhibitors

摘要: This invention relates to novel intermediate compounds which are useful for producing the halogenated protese inhibitors that subject matter of U.S. Patent 4,469,885. In particular, methods and intermediates making said protease inhibitors, being formula: wherein R₁ is: (a) straight or branched chain lower alkyl having 1-6 carbon atoms; (b) H; R₆ higher 13-25 alkenyl R₅ benzyl; R₇ R₂ -Cl, Br, -I; -CF₃.