Genetic Definition and Sequence Analysis of Arabidopsis Centromeres
作者： Gregory P Copenhaver , Kathryn Nickel , Takashi Kuromori , Maria-Ines Benito , Samir Kaul
DOI: 10.1126/SCIENCE.286.5449.2468
关键词:
摘要: High-precision genetic mapping was used to define the regions that contain centromere functions on each natural chromosome in Arabidopsis thaliana. These exhibited dramatic recombinational repression and contained complex DNA surrounding large arrays of 180-base pair repeats. Unexpectedly, within centromeres not merely structural but also encoded several expressed genes. The flanking were densely populated by repetitive elements yet experienced normal levels recombination. genetically defined well conserved among ecotypes displayed limited sequence homology between different chromosomes, excluding DNA. This investigation provides a platform for dissecting role individual sequences higher eukaryotes.
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