Physiology of cardiovascular gap junctions.
作者： Toon A.B. van Veen, , Harold V.M. van Rijen , Habo J. Jongsma
DOI: 10.1159/000092560
关键词:
摘要: Cardiac gap junction channels are crucial for conduction of the electric impulse. Between cardiomyocytes there exist junctions constructed from connexin40 (Cx40), Cx43 and Cx45. A fourth isoform, Cx37, is expressed in endothelial lining. Each these channel types possesses specific properties their functioning regulated by various mechanisms. In this chapter we compare physiological differences between discuss factors involved modulation properties. Next, evaluate how alterations expression differential regulation affect cardiac impulse propagation.
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