CBL-CIPK module-mediated phosphoregulation: facts and hypothesis.

摘要: Calcium (Ca2+) signaling is a versatile network in plant and employs very efficient signal decoders to transduce the encoded message. The CBL-CIPK module one of sensor-relay that have probably evolved with acclimatization land plant. CBLs are unique proteins non-canonical Ca2+ sensing EF-hands, N-terminal localization motif C-terminal phosphorylation motif. partner CIPKs Ser/Thr kinases kinase regulatory domains. Phosphorylation plays major role functioning module. As has functional signal, it as preferred mode for modulation targets well its interaction CBL. We analyze data on substrate regulation by from perspective phosphorylation. also predicted some probable sites identified substrates may be target CIPK mediated In addition, phosphatases been implicated reversing substrates. Therefore, we presented targets. present here an overview phosphoregulation mechanism