Activation of human ovarian cancer cells: role of lipid factors in ascitic fluid

摘要: Normal cells proliferate in response to injury or replace with a limited survival time. This is true for the hematopoietic system and epithelial of skin bowel. It has been estimated that 1 million cell divisions per second are required replacement lost cells. The proliferation normal regulated by action number polypeptide lipid factors called growth [1–8]. These bind specific surface receptors transmit activation signals across membrane. initiate intracellular biochemical cascades which turn communicate nucleus, eventually leading cellular [5–8]. In addition positive signals, series proteins involved limiting [9–10]. Several these, such as p53 product retinoblastoma gene (RB), more commonly known tumor suppressor genes [9,10]. Finally, some activated sensitized physiological process Known programmed death apoptosis [11–13]. Both products must be overcome divide.