作者: L. Carrasco , J. Hervas , J. C. Gomez-Villamandos , F. Chacon , M. de Lara
DOI: 10.1136/VR.140.3.72
关键词:
摘要: Transdermally administered fentanyl in dogs TRANSDERMAL drug delivery systems have many potential advantages. In a study healthy beagles, transdermal patch, applied to the dorsal thoracic skin, was designed deliver dose of 50 rg/h for 72 hours. Fentanyl estimated plasma using radioimmunoassay. The patch produced average steady state concentrations 1-6 mg/ml. actual transder- mal 35.7 (range 13-7 49-8) ,ug/hour, which repre- sented 71-48 per cent 27-45 99-56 cent) theo- retical rate delivery. mean elimination half-life after removal 1-39 This technique has postoperative analgesia, and further evaluation is warranted. KYLES, A. E., PAPICH, M. & HARDIE, E. (1996) American Journal Veterinary Research 57, 715 Treatment regimes bovine papillomatous digital dermatitis FORTY-EIGHT cows with were randomly assigned one four treatment groups: oxytetracy- cline solution (100 mg/ml), acidified ionised copper (Hoof Pro Plus; SSI Corporation), sodium chlorite solu- tion (Prototype alcide hoof treatment; Alkide Corporation) or tap water. area, treated three times daily, first washed clean then sprayed (5 ml dose). lameness score (graded 0 [not lame] 3 [severely lame]) decreased by 0-6, 1.1 0-8 units respectively antibiotic, groups increased 0-6 water-treated controls. did not eradicate lesions herd, had prevalence about 15 dermatitis. BRIlTT, J. S., GASKA, J., GARRETT, F., KONKLE, D. MEALY, Medical Association 209, 1134 73