OPTIMAL CONTROL OF THE SPREAD OF MALARIA SUPERINFECTIVITY

摘要: Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected mosquitoes. In this paper, deterministic model for malaria transmission, incorporates superinfection presented. Qualitative analysis reveals presence backward bifurcation in which stable disease-free equilibrium co-exists with endemic when associated reproduction threshold less than unity. Optimal control theory then applied study time-dependent treatment efforts minimize individuals while keeping implementation cost at minimum.