N-(9-acridinyl)-bromoacetamide--a powerful reagent for phase-transfer-catalyzed fluorescence labeling of carboxylic acids for liquid chromatography.
作者： Stig Allenmark , Monika Chelminska-Bertilsson , Richard A. Thompson
DOI: 10.1016/0003-2697(90)90293-I
关键词:
摘要: Abstract Phase-transfer-catalyzed esterification of various carboxylic acids has been carried out on a microanalytical scale with new reagent, N-(9-acridinyl)-bromoacetamide, in aqueous/organic two-phase systems. The procedure gives esters showing very high fluorescence intensity acid solution. large Stokes' shift (>120 nm) means that low background can be achieved even when using emission bandwidth. These derivatives show good chromatographic behavior reversed-phase liquid columns the use aqueous acetonitrile, containing 0.2% phosphoric acid, as mobile phase. Detection limits ( S N = 2 ) 10 fmol obtained under optimal conditions.
elsevier.com
sci-hub.se 参考文章(21)
Wolfgang D�nges, Axel Meyer, Karl-Erhard M�ller, Margit M�ller, Rainer Pietschmann, Christoph Plachetta, R�diger Sehr, Hedwig Tuss, Fluorescence labelling of organic acidic compounds with 4-bromomethyl-7-methoxycoumarin (Br-Mmc) Fresenius Journal of Analytical Chemistry. ,vol. 288, pp. 361- 368 ,(1977) , 10.1007/BF00433754
Masatoshi Yamaguchi, Shuuji Hara, Reiko Matsunaga, Masaru Nakamura, Yosuke Ohkura, 3-Bromomethyl-6,7-dimethoxy-1-methyl-2(1H)-quinoxalinone as a new fluorescence derivatization reagent for carboxylic acids in high-performance liquid chromatography Journal of Chromatography A. ,vol. 346, pp. 227- 236 ,(1985) , 10.1016/S0021-9673(00)90508-9
Hironori Tsuchiya, Tokishi Hayashi, Hiroshi Naruse, Nobuhiko Takagi, High-performance liquid chromatography of carboxylic acids using 4-bromomethyl-7-acetoxycoumarin as fluorescence reagent Journal of Chromatography A. ,vol. 234, pp. 121- 130 ,(1982) , 10.1016/S0021-9673(00)81786-0
Wolfgang. Duenges, 4-Bromomethyl-7-methoxycoumarin as a new fluorescence label for fatty acids Analytical Chemistry. ,vol. 49, pp. 442- 445 ,(1977) , 10.1021/AC50011A028
R. Farinotti, Ph. Siard, J. Bourson, S. Kirkiacharian, B. Valeur, G. Mahuzier, 4-bromomethyl-6,7-dimethoxycoumarin as a fluorescent label for carboxylic acids in chromatographic detection Journal of Chromatography A. ,vol. 269, pp. 81- 90 ,(1983) , 10.1016/S0021-9673(01)90788-5
Satoru Kamada, Masako Maeda, Akio Tsuji, Fluorescence high-performance liquid chromatographic determination of free and conjugated bile acids in serum and bile using 1-bromoacetylpyrene as a pre-labeling reagent Journal of Chromatography B: Biomedical Sciences and Applications. ,vol. 272, pp. 29- 41 ,(1983) , 10.1016/S0378-4347(00)86100-9
W.D. Korte, 9(chloromethyl)anthracene: a useful derivatizing reagent for enhanced ultraviolet and fluorescence detection of carboxylic acids with liquid chromatography Journal of Chromatography A. ,vol. 243, pp. 153- 157 ,(1982) , 10.1016/S0021-9673(00)88175-3
AKIRA TAKADATE, TSUTOMU TAHARA, HIROYUKI FUJINO, SHUJIRO GOYA, Synthesis and Properties of 4-Diazomethyl-7-methoxycoumarin as a New Fluorescent Labeling Reagent for Alcohols and Carboxylic Acids Chemical & Pharmaceutical Bulletin. ,vol. 30, pp. 4120- 4125 ,(1982) , 10.1248/CPB.30.4120
Andreas Furängen, Extractive alkylation of fatty acids with phenacyl bromide, studied by liquid chromatography Journal of Chromatography A. ,vol. 353, pp. 259- 271 ,(1986) , 10.1016/S0021-9673(01)87095-3
Stig Allenmark, Monika Chelminska-Bertilsson, Determination of carboxylic acids by liquid chromatography after phase-transfer-catalysed fluorogenic labelling Journal of Chromatography A. ,vol. 456, pp. 410- 416 ,(1988) , 10.1016/0021-9673(86)80040-1