Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
作者： Thomas Schindler , William Bornmann , Patricia Pellicena , W Todd Miller , Bayard Clarkson
DOI: 10.1126/SCIENCE.289.5486.1938
关键词:
摘要: … Abl, complexed to a variant of STI-571. Critical to the binding of STI-571 is the adoption by … The inhibitor that we have crystallized differs from STI-571 in that it lacks a piperazinyl group …
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