Generators of the intracranial P50 response in auditory sensory gating
作者： Oleg Korzyukov , Mark E. Pflieger , Michael Wagner , Susan M. Bowyer , T. Rosburg
DOI: 10.1016/J.NEUROIMAGE.2006.12.011
关键词:
摘要: Abstract Clarification of the cortical mechanisms underlying auditory sensory gating may advance our understanding brain dysfunctions associated with schizophrenia. To this end, data from nine epilepsy patients who participated in an paired-click paradigm during pre-surgical evaluation and had grids electrodes covering temporal frontal lobe were analyzed. A distributed source localization approach was applied to intracranial P50 response Gating Difference Wave obtained by subtracting second stimuli first stimuli. Source reconstruction showed that main generators localized lobes. The analysis also suggested maximum neuronal activity contributing amplitude reduction time range (phenomenon gating) is at lobe. Present findings suggest while generator component, seems be a substantial contributor process as observed scalp recordings.
elsevier.com
sci-hub.se 参考文章(52)
R D Pascual-Marqui, Review of methods for solving the EEG inverse problem Int J Bioelectromagnetism. ,vol. 1, ,(1999)
Jerome Engel, Timothy A Pedley, Jean Aicardi, None, Epilepsy : a comprehensive textbook Lippincott Williams & Wilkins. ,(2008)
Risto Näätänen, Attention and brain function ,(1992)
J.C Edgar, M.X Huang, M.P Weisend, A Sherwood, G.A Miller, L.E Adler, J.M Cañive, Interpreting abnormality: an EEG and MEG study of P50 and the auditory paired-stimulus paradigm. Biological Psychology. ,vol. 65, pp. 1- 20 ,(2003) , 10.1016/S0301-0511(03)00094-2
Marina Myles-Worsley, Hilary Coon, William Byerley, Merilyne Waldo, David Young, Robert Freedman, Developmental and genetic influences on the p50 sensory gating phenotype Biological Psychiatry. ,vol. 39, pp. 289- 295 ,(1996) , 10.1016/0006-3223(95)00134-4
C. Liégeois-Chauvel, A. Musolino, J.M. Badier, P. Marquis, P. Chauvel, Evoked potentials recorded from the auditory cortex in man : evaluation and topography of the middle latency components Electroencephalography and Clinical Neurophysiology. ,vol. 92, pp. 204- 214 ,(1994) , 10.1016/0168-5597(94)90064-7
Norman Tepley, MEG: good enough-a response. Clinical Neurophysiology. ,vol. 116, pp. 236- 237 ,(2005) , 10.1016/J.CLINPH.2004.07.014
Kristin Jerger, Christie Biggins, George Fein, P50 suppression is not affected by attentional manipulations Biological Psychiatry. ,vol. 31, pp. 365- 377 ,(1992) , 10.1016/0006-3223(92)90230-W
Brett Clementz, Laura Blumenfeld, Multichannel electroencephalographic assessment of auditory evoked response suppression in schizophrenia. Experimental Brain Research. ,vol. 139, pp. 377- 390 ,(2001) , 10.1007/S002210100744
JP Mäkelä, M Hämäläinen, R Hari, L McEvoy, None, Whole-head mapping of middle-latency auditory evoked magnetic fields ☆ Electroencephalography and Clinical Neurophysiology. ,vol. 92, pp. 414- 421 ,(1994) , 10.1016/0168-5597(94)90018-3