Prognostic value of pre- and post-treatment health-related quality of life in predicting survival of patients with brain metastases.

作者: Erin Wong , Leigha Rowbottom , May Tsao , Liying Zhang , Rachel McDonald

DOI: 10.2217/CNS-2016-0020

关键词:

摘要: Aim: The present study aimed to determine the prognostic survival value of pretreatment health-related quality life (HRQOL) and changes in HRQOL following whole-brain radiation treatment patients with brain metastases. Methods: Patients who were treated completed questionnaires included. Univariate multivariate Cox proportional hazard models overall (OS) conducted for domain scores. Results & conclusion: lower at baseline, especially physical functioning motor dysfunction domains, more likely have poorer survival. Changes its domains not significantly related OS. Pretreatment HRQOL, dysfunction, has added

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