Diagnostic Utility of Thyroglobulin Detection in Fine-Needle Aspiration of Cervical Cystic Metastatic Lymph Nodes from Papillary Thyroid Cancer with Negative Cytology

摘要: Cystic changes in metastatic cervical lymph nodes (CLN) from papillary thyroid cancer (PTC) may be a diagnostic pitfall fine-needle aspiration biopsy (FNAB) cytology. We investigated series of CLN metastases cancers (TC), including cystic PTC, and wide spectrum extrathyroidal malignancies, the role for TC rapid detection thyroglobulin eluates FNAB (FNAB-Tg) CLN. The study was carried out group 79 subjects (22/57 M/F; median age, 56 years; range, 20-86 years) with enlarged nodules (TN), examined potential TC, harboring large incidentally diagnosed malignancies (n = 24, mostly represented by lymphomas, lung, breast cancers), 28, 6 PTC), specific lymphadenitis 21 reactive detected 16) during follow-up patients previously ablated TC. Markedly high (Tg) values were found all Two six cases PTC FNAB-Tg but not In conclusion, has been confirmed as an easy modality fast procedure to diagnose metastasis nondiagnostic cytology strongly suggest PTC.