Oncogenic regulatory rnas for diagnostics and therapeutics
作者： Matthias Wabl , Bruce Wang
DOI:
关键词:
摘要: A method of identifying regulatory RNAs, including miRNAs, using insertional mutagenesis to generate tumors in mice and determining the human orthologs is disclosed. Further, specific miRNA sequences are identified. The causal nature expression patterns these RNAs miRNAs demonstrate their utility diagnosis therapy cancer. Furthermore, a set co-mutations that act conjunction with tumor formation
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