Use of microorganisms for the study of drug metabolism: an update.

作者: Alice M. Clark , Charles D. Hufford

DOI: 10.1002/MED.2610110503

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摘要: … This means that a relatively large number of microorganisms can be screened simultaneously for their ability to metabolize the drug substrate. In addition, the concentrations of drug …

参考文章(77)
Tannis M. Jürgens, Alice M. Clark, The metabolism of CGP-291: the use of microorganisms as models of mammalian metabolism. Pharmaceutical Research. ,vol. 7, pp. 742- 745 ,(1990) , 10.1023/A:1015871723330
Alice M. Clark, James D. McChesney, Charles D. Hufford, Fungal metabolism of 4-methylprimaquine. Pharmaceutical Research. ,vol. 3, pp. 170- 172 ,(1986) , 10.1023/A:1016318125534
John P. Rosazza, Robert V. Smith, Microbial models for drug metabolism. Advances in Applied Microbiology. ,vol. 25, pp. 169- 208 ,(1979) , 10.1016/S0065-2164(08)70150-3
Bernard Testa, Peter Jenner, Concepts in drug metabolism M. Dekker. ,(1980)
J. W. Faigle, A. D. Coutinho, H. Keberle, F. Trindade Barretto, The metabolism of niridazole (AMBILHARR) in man. II. Investigations on patients suffering from clinically advanced forms of Schistosoma mansoni infection. Annals of Tropical Medicine and Parasitology. ,vol. 64, pp. 383- 393 ,(1970) , 10.1080/00034983.1970.11686708
Mamoru Kurachi, Takaya Mio, On the Formation of a Conjugate of PCBs with Glutathione and Its Further Metabolism in Mice or Rats Agricultural and biological chemistry. ,vol. 47, pp. 1193- 1199 ,(1983) , 10.1271/BBB1961.47.1193
K B Frank, J F Chiou, Y C Cheng, Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate. Journal of Biological Chemistry. ,vol. 259, pp. 1566- 1569 ,(1984) , 10.1016/S0021-9258(17)43446-6